CD11c – RMab

SKU: b1eca794123b Categories: , ,


IHC of CD11c on an FFPE Spleen Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationCD11c (1TGAX) is a member of the leukointegrin family and shares the same beta subunit with other members of the leukocyte adhesion molecule family, which include CD11a (LFA-1), CD11b (MAC-1), and CD11d (ITGAD), but has a unique alpha chain. CD11c is a type I transmembrane protien found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells that induces cellular activation and helps trigger neutrophil respiratory burst.
CD11c is expressed in Hairy Cell leukemias, Acute Nonlymphocytic Leukemias, and some B-cell Chronic Lymphocytic Leukemias.
Antibody TypeRabbit MonoclonalCloneEP157
IsotypeIgGReactivityParaffin, Frozen
LocalizationCytoplasmicControlBone Marrow, Spleen, Tonsil, Colon, Hairy Cell
PresentationCd11c is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 6443PredilutedReady-To-Use3.0 ml
BSB 6444PredilutedReady-To-Use7.0 ml
BSB 6445PredilutedReady-To-Use15.0 ml
BSB 6446Concentrated1:25-1:500.1 ml
BSB 6447Concentrated1:25-1:500.5 ml
BSB 6448Concentrated1:25-1:501.0 ml
BSB 6449Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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