IHC of CA-125 on an FFPE Ovarian Carcinoma Tissue
| Intended Use | For In Vitro Diagnostic Use | |||||||||||||||||||||||||||||||||||
| Summary and Explanation | CA-125 reacts with malignant ovarian epithelial cells. CA-125 also reacts with antigens in Seminal Vesicle Carcinoma and Anaplastic Lymphoma. In adult tissues, CA-125 is found in epithelial cells of Fallopian tube, endometrium and endocervix, pancreas, colon, gall bladder, stomach, kidney, apocrine sweat gland, and mammary gland. It is also found in mesothe- lial cell lining of pleura, pericardium and peritoneum. It is found in ovarian tumors of serous, endometrioid or clear-cell types and Adenocarcinomas of Mullerian type. |
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| Antibody Type | Rabbit Monoclonal | Clone | EP48 | |||||||||||||||||||||||||||||||||
| Isotype | IgG | Reactivity | Paraffin, Frozen | |||||||||||||||||||||||||||||||||
| Localization | Membranous, Cytoplasmic | Control | Colon, Pancreas, Epitheliod Mesothelioma, Ovarian Carcinoma | |||||||||||||||||||||||||||||||||
| Presentation | CA-125 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative. | |||||||||||||||||||||||||||||||||||
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| Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product. | ||||||||||||||||||||||||||||||||||||
