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Thyroglobulin – BSB-49 – MMab

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IHC of Thyroglobulin on an FFPE Thyroid Tissue

IHC of Thyroglobulin on an FFPE Thyroid Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation Thyroglobulin (Tg) is a 660 kDa, dimeric protein produced by and used entirely within the thyroid gland. Tg is used by the thyroid gland to produce the thyroid hormones thyroxine (T4) and triiodothyronine (T3). The active form of thyroxine, triiodothyronine, is produced both within the thyroid gland and on the periphery by-5’-deiodinase, which has been referred to as Tetraiodothyronine-5-deiodinase. This antibody reacts with human thyroglobulin as demonstrated by a single band of immunoblotting in alysate of human thyroid tissue. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for thyroglobulin, sometimes only focally. Poorly-differentiated Carcinomas of the Thyroid are frequently thyroglobulin negative. Adenocarcinomas of non-thyroid origin do not react with this antibody.
Antibody Type Mouse Monoclonal Clone BSB-49
Isotype IgG1 Reactivity Paraffin, Frozen
Localization Cytoplasmic Control Thyroid, Thyorid Carcinoma
Presentation Thyroglobulin is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 5973 Prediluted Ready-To-Use 3.0 ml
BSB 5974 Prediluted Ready-To-Use 7.0 ml
BSB 5975 Prediluted Ready-To-Use 15.0 ml
BSB 5976 Concentrated 1:250-1:1000 0.1 ml
BSB 5977 Concentrated 1:250-1:1000 0.5 ml
BSB 5978 Concentrated 1:250-1:1000 1.0 ml
BSB 5979 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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