Ki-67 – RMab

Ihc Of Ki-67 On An Ffpe Hsil Of The Cervix

IHC of Ki-67 on an FFPE Colon Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationThe Ki-67 protein is a cellular marker for proliferation. It is strictly associated with cell proliferation. During the interphase, the Ki-67 antigen can be exclusively detected within the cell nucleus, whereas in mitosis most of the protein is relocated to the surface of the chromosomes. Ki-67 protein is present during all active phases of the cell cycle (G1, S, G2, and mitosis), but is absent from resting cells (G0). Ki-67 is an excellent marker to determine the growth fraction of a given cell population. The fraction of Ki-67-positive tumor cells (the Ki-67 labeling index) is often correlated with the clinical course of cancer. The best-studied examples in this context are Carcinomas of the Prostate and the Breast.
Antibody TypeRabbit MonoclonalCloneEP5
IsotypeIgGReactivityParaffin, Frozen
LocalizationNuclearControlTestis, Tonsil, Bone Marrow, Placenta, colon, Tonsil, Fallopian tube, Astrocytoma, Breast Carcinoma, Colon Carcinoma
PresentationKi-67 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 5708PredilutedReady-To-Use3.0 ml
BSB 5709PredilutedReady-To-Use7.0 ml
BSB 5710PredilutedReady-To-Use15.0 ml
BSB 5711Concentrated1:25-1:1000.1 ml
BSB 5712Concentrated1:25-1:1000.5 ml
BSB 5713Concentrated1:25-1:1001.0 ml
BSB 5714Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
* The Ki-67 antibody, clone EP5, has been manufactured using Epitomics RabMab® technology covered under Patent No.’s 5,675,063 and 7,402,409.

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