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Insulin – RMab

Ihc Of Insulin On An Ffpe Pancreas Tissue

IHC of Insulin on an FFPE Pancreas Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationInsulin is produced in the beta cells of the Islets of Langerhans in the pancreas. It is a polypeptide hormone that regulates carbohydrate metabolism. Apart from being the primary agent in carbohydrate homeostasis, insulin has effects on fat metabolism and changes the liver’s ability in storing or releasing glucose and processing blood lipids, and in other tissues such as fat and muscle. The amount of insulin in circulation has extremely widespread effects throughout the body.
The presence of insulin in the cytoplasm of Islet Tumors is the most reliable indication of functional Insulinomas. Defective insulin storage occurs in Insulinomas; therefore, many sections of the tumor should be stained with both insulin and C-peptide.
Antibody TypeRabbit MonoclonalCloneEP125
IsotypeIgGReactivityParaffin, Frozen
LocalizationCytoplasmicControlPancreas
PresentationInsulin is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 6835PredilutedReady-To-Use3.0 ml
BSB 6836PredilutedReady-To-Use7.0 ml
BSB 6837PredilutedReady-To-Use15.0 ml
BSB 6838Concentrated1:50-1:2000.1 ml
BSB 6839Concentrated1:50-1:2000.5 ml
BSB 6840Concentrated1:50-1:2001.0 ml
BSB 6841Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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