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GFAP – RMab

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IHC of GFAP on an FFPE Brain Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation Glial fibrillary acidic protein or GFAP is a Type III protein of the intermediate filaments principally found in astrocytes in the central nervous system, but can also be found in neurons, hepatic stellate cells, kidney mesangial cells, pancreatic stellate cells, and Leydig cells. It has a role in the cytoskeleton of the astrocyte and possibly many other stellate-shaped cells.
Antibodies to GFAP are very useful as markers of astrocytic cells. In addition, many types of brain tumors, presumably derived from astrocytic cells, heavily express GFAP. This marker is mainly used to distinguish neoplasms of astrocytic origin from other neoplasms in the central nervous system.
Antibody Type Rabbit Monoclonal Clone EP13
Isotype IgG Reactivity Paraffin, Frozen
Localization Cytoplasmic Control Brain
Presentation GFAP is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 6772 Prediluted Ready-To-Use 3.0 ml
BSB 6773 Prediluted Ready-To-Use 7.0 ml
BSB 6774 Prediluted Ready-To-Use 15.0 ml
BSB 6775 Concentrated 1:25-1:100 0.1 ml
BSB 6776 Concentrated 1:25-1:100 0.5 ml
BSB 6777 Concentrated 1:25-1:100 1.0 ml
BSB 6778 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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