Cytokeratin HMW 34BetaE12 – MMab

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Ck Hmw 34Be12 Mmab

IHC of CK34BE12 on an FFPE Prostate Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationCytokeratin 34βE12 is a High Molecular Weight cytokeratin that reacts with all squamous and ductal epithelium and stains carcinomas. This antibody recognizes cytokeratins 1, 5, 10, and 14 that are found in complex epithe-lia. Cytokeratin 34βE12 shows no reactivity with hepatocytes, pancreatic acinar cells, proximal renal tubules or endometrial glands; there has been no reactivity with cells derived from simple epithelia. Nerve cells, glial cells and mesenchymal tissue such as blood vessels containing only non-keratin types of intermediate filaments are not labelled; however, reactivity with smooth-muscle cells has been occasionally observed. Mesenchymal Tumors, Lymphomas, Melanomas, Neural Tumors and Neuroendocrine Tumors are unreactive with this antibody. Cytokeratin 34βE12 has been shown to be useful in distinguishing Prostatic Adenocarcinoma from Hyperplasia of the Prostate.
Antibody TypeMouse MonoclonalClone34BE12
IsotypeIgG1/KReactivityParaffin, Frozen
LocalizationCytoplasmicControlProstate, Cervix
PresentationCytokeratin 34βE12 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 5393PredilutedReady-To-Use3.0 ml
BSB 5394PredilutedReady-To-Use7.0 ml
BSB 5395PredilutedReady-To-Use15.0 ml
BSB 5396Concentrated1:50-1:2000.1 ml
BSB 5397Concentrated1:50-1:2000.5 ml
BSB 5398Concentrated1:50-1:2001.0 ml
BSB 5399Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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