IHC of Cytokeratin 13 on an FFPE Cervix Tissue
| Intended Use | For In Vitro Diagnostic Use | |||||||||||||||||||||||||||||||||||
| Summary and Explanation | Cytokeratin 13 is a type I cytokeratin usually paired with Cytokeratin 4 and is found in the suprabasal layers of non-cornified stratified epithelia such as tongue mucosa, esophagus, anal canal epithelium, tracheal epithelium, uterine cervix, and urothelium. Anti-Cytokeratin 13 has been used as a marker for Non-Keratinzed Squamous Epithelium and can also be expressed in Squamous Metaplasia, but is down regulated in Squamous Dysplasia and Squamous Carcinoma. | |||||||||||||||||||||||||||||||||||
| Antibody Type | Rabbit Monoclonal | Clone | EP69 | |||||||||||||||||||||||||||||||||
| Isotype | IgG | Reactivity | Paraffin, Frozen | |||||||||||||||||||||||||||||||||
| Localization | Cytoplasmic | Control | Uterine Cervix, Urothelium | |||||||||||||||||||||||||||||||||
| Presentation | CK13 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative. | |||||||||||||||||||||||||||||||||||
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| Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product. | ||||||||||||||||||||||||||||||||||||
