CD41/Integrin alpha IIb – RMab

SKU: 571c886cc426 Categories: , , ,

Cd41 40X 1Mdk13 47 2 Bone Marrow

IHC of CD41/Integrin alpha lib on a FFPE Spleen Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationITGA2B encodes CD41, or integrin alpha IIb. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain IIb undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibrinogen receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface medicated signalling.
CD41 expression has been found on platelets, megakaryocyes, and immature hematopoietic progenitors.
Antibody TypeRabbit MonoclonalCloneEP178
IsotypeIgGReactivityParaffin, Frozen
LocalizationMembranous, CytoplasmicControlBone Marrow, Spleen
PresentationCD41 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 6506PredilutedReady-To-Use3.0 ml
BSB 6507PredilutedReady-To-Use7.0 ml
BSB 6508PredilutedReady-To-Use15.0 ml
BSB 6509Concentrated1:25-1:1000.1 ml
BSB 6510Concentrated1:25-1:1000.5 ml
BSB 6511Concentrated1:25-1:1001.0 ml
BSB 6512Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
Specification Sheets
Safety Data Sheet

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