CD15 – MMab

SKU: 3023e8a6ab39 Categories: , , ,


IHC of CD15 on an FFPE Hodgkin’s Lymphoma Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationCD15 is a phosphatidylinositol-anchored transmembrane protein found on neutrophils and which may be involved in phagocytosis. It is expressed in patients with Hodgkin’s Disease, some B-cell Chronic Lymphocytic Leukemias, Acute Lymphoblastic Leukemias, and most Acute Non-Lymphocytic Leukemias. It is also called Lewis x. A positive reaction for CD15 combined with a negative reaction for CD45 and other B and T-lineage markers provides support for Reed-Sternberg cells found in Hodgkin’s disease. Also, this antibody does not detect Mesotheliomas, making it a more frequently used antibody to distinguish Epithelial Mesothelioma from Adenocarcinoma.
Antibody TypeMouse MonoclonalCloneMMA
IsotypeIgMReactivityParaffin, Frozen
LocalizationCytoplasmic, MembranousControlTonsil, Lymph Node, Hodgkin’s Lymphoma
PresentationCD15 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 5183PredilutedReady-To-Use3.0 ml
BSB 5184PredilutedReady-To-Use7.0 ml
BSB 5185PredilutedReady-To-Use15.0 ml
BSB 5186Concentrated1:25-1:1000.1 ml
BSB 5187Concentrated1:25-1:1000.5 ml
BSB 5188Concentrated1:25-1:1001.0 ml
BSB 5189Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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