Melanosome – MMab

SKU: be98645e2e42 Categories: , ,

Melanosome Ab Mmab

IHC of Melanoma / HMB-45 on an FFPE Malignant Melanoma Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationHMB-45 reacts against an antigen present in immature melanosomes, cutaneous melanocytes, prenatal and infantile retinal pigment epithelium cells. This antibody was generated to an extract of Melanoma. It reacted positively against Melanocytic Tumors but not other tumors, thus demonstrating specificity and sensitivity. Moreover, this antibody reacts positively against juntional nebus cells but not intradermal nevi, and against fetal melanocytes but not normal adult melanocytes.This antibody is very useful to identify Malignant Melanoma. Metastatic Amelanotic Melanoma can often be confused with a variety of poorly differentiated Carcinomas, Large Cell Lymphomas, Sarcomas, Spindle Cell Carcinomas and various types of mesenchymal neoplasms. A keratin-negative, vimentin-rich neoplasm that immunoreacts with antibody to S-100 protein and with this melanoma antibody, is, with rare exception, a Melanoma.
Antibody TypeMouse MonoclonalCloneHMB-45
IsotypeIgG1/KReactivityParaffin, Frozen
PresentationHMB-45 Melanoma antibody is a mouse monoclonal from tissue culture supernatant that is diluted in Phosphate Buffered Saline, pH 7.6, with protein base, and preserved with Sodium Azide preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 5757PredilutedReady-To-Use3.0 ml
BSB 5758PredilutedReady-To-Use7.0 ml
BSB 5759PredilutedReady-To-Use15.0 ml
BSB 5760Concentrated1:250-1:10000.1 ml
BSB 5761Concentrated1:250-1:10000.5 ml
BSB 5762Concentrated1:250-1:10001.0 ml
BSB 5763Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

Related products

Skip to content