Carbonic Anhydrase 9 – RMab

Carbonic Anhydrase 9

IHC of Carbonic Anhydrase 9 on an FFPE Kidney Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationCarbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calicification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization.
CA9 is a transmembrane protein and the only tumor-associated CA isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be invovled in cell proliferation and transformation. CA9 is considered to be one of the best cellular biomarkers of hypoxic regions in many solid regions.
Antibody TypeRabbit MonoclonalCloneEP 161
IsotypeIgGReactivityParaffin, Frozen
LocalizationMembranous and CytoplasmicControlStomach, Gallbladder, Kidney Carcinoma, Cervix Carcinoma, Lung carcinoma
PresentationCarbonic Anhydrase 9 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 6415PredilutedReady-To-Use3.0 ml
BSB 6416PredilutedReady-To-Use7.0 ml
BSB 6417PredilutedReady-To-Use15.0 ml
BSB 6418Concentrated1:25-1:1000.1 ml
BSB 6419Concentrated1:25-1:1000.5 ml
BSB 6420Concentrated1:25-1:1001.0 ml
BSB 6421Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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