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ACTH – MMab

Category:
Intended UseFor In Vitro Diagnostic Use
Summary and ExplanationAdrenocorticotropic Hormone (ACTH or corticotropin) is a polypeptide hormone synthesized from POMC, (Pro-opiomelanocortin) and secreted from corticotropes in the anterior lobe of the pituitary gland in response to Corticotropin-releasing Hormone (CRH) released by the hypothalamus. It consists of 39 amino acids. ACTH is a useful marker in the classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs), as well as other tumors (e.g.,some Small-Cell Carcinomas present in lung tissue) causing Paraneoplastic Syndromes by secreting ACTH.
Antibody TypeMouse MonoclonalCloneBSB-25
IsotypeIgG1/KReactivityParaffin, Frozen
LocalizationCytoplasmicControlNormal Pituitary
PresentationACTH is a purified immunoglobulin fraction of rabbit antiserum that is filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 5015PredilutedReady-To-Use3.0 ml
BSB 5016PredilutedReady-To-Use7.0 ml
BSB 5017PredilutedReady-To-Use15.0 ml
BSB 5018Concentrated1:250-1:10000.1 ml
BSB 5019Concentrated1:250-1:10000.5 ml
BSB 5020Concentrated1:250-1:10001.0 ml
BSB 5021Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.

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